What is MCN?

Mucinous cystic neoplasm, Cystic tumors of pancreas, less common than IPMN and SCNs. Most are thick-walled cysts with septations filled with mucus. Clinical spectrum may be benign to malignant, so they require histologic presence of ovarian type stroma within the tumor to get a dx of MCN 72% benign adenomas, 10% borderline, 5% carcinoma, 12% invasive cancers. Female predominant (20:1), confined to body and tail of pancreas, age of presentation is 50 MRCP shows no connection between pancreatic duct and the cyst EUS identifies septa, and allows cyst wall biopsy/aspiration (thick mucoid material, low amylase, elevate CEA, mucinous epithelia on histology) differentiate it from SCN (low CEA) and IPMN (high amylase)