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Endocrinology

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Question:

What is the difference between hetero familial hypercholesterolemia and homo?

Author: H K



Answer:

LDL (Hetero [200-500], Homo >500) Total cholesterol (Hetero [300-500], Homo [500-1000]) LDL receptors (hetero half are still normal, homo no receptors) CHD (hetero btw 30-50 years, homo at age 10 and rare survival to age 20) Response To Therapy (hetero respond to activators of LDL Recpetors, Homo no response)


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H K
H K