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Endocrinology

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Question:

What are primary causes of chylomicronemias?

Author: H K



Answer:

FCS (most common, LPL deficiency or ApoCII deficiency or LPL inhibitors, cause infancy HyperTG low tolerance to fat) Familial combined hyperlipidemia (FCHL) (increased VLDL and TG and IDL and LDL and CT and decreased HDL) Familial hypertriglyceridemia (FHTG) (increased VLDL and TG and decreased HDL, with normal LDL IDL and CT) Dysbetalipoproteinemia (remnant removal disease, Type III hyperlipoproteinemia, defect ApoE, accumulation of remnant VLDL and chylomicrons (VLDL and TG high, LDL CT high , HDL low)


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H K
H K