(STEP 1 --- DELIVERY: FROM THE SITE OF EXPOSURE TO THE TARGET) ULTIMATE TOXICANT 1 Its INCREASED CONCENTRATION is facilitated by __ 2 DECREASED CONCENTRATION is facilitated by __

. 1 - Absorption, - Distribution to the site of action, - Reabsorption, and - Toxication ADR T 2 - Presystemic elimination, - Distribution away from the site of action, - Excretion, and - Detoxication. PDED