TOXICOLOGY: (Sustained Rise of Intracellular Ca2+)

Sustained elevation of intracellular Ca2+
is harmful because it can result in:

Question

(Sustained Rise of Intracellular Ca2+)

Sustained elevation of intracellular Ca2+
is harmful because it can result in:

LEIGHTON DWIGHT OBILLOS · Accepted Answer

1 DEPLETION OF ENERGY reserves by inhibiting the ATPase used in oxidative phosphorylation,

2 DYSFUNCTION of microfilaments

3 ACTIVATION OF HYDROLYTIC ENZYMES

4 Generation of ROS and RNS

(Sustained Rise of Intracellular Ca2+) Sustained elevation of intracellular Ca2+ is harmful because it can result in: