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TOXICOLOGY

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Question:

A. MOLECULAR REPAIR (Repair of Proteins) 1 occurs by means of electron transfer from cytochrome b5, which is then regenerated by a NADH dependent cytochrome b5 reductase. 2 are synthesized in large quantities in RESPONSE TO PROTEIN DENATURATION 3 Damaged proteins can either be __, following ubiquitination in proteasomes. 4 Proteins can be eliminated by __ in lysosomes.

Author: LEIGHTON DWIGHT OBILLOS



Answer:

. 1 Repair of oxidized hemoglobin (methemoglobin) 2 Molecular chaperones such as the heatshock proteins 3 refolded with the help of chaperone proteins or degraded 4 proteolysis


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