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TOXICOLOGY

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Question:

C. TISSUE REPAIR (Side Reactions to Tissue Injury) a) Inflammation 1 Alteration of the microcirculation and accumulation of inflammatory cells are largely initiated by resident MACROPHAGES SECRETING CYTOKINES such as __ in response to tissue damage. 2 These cytokines, in turn, stimulate neighboring stromal cells, such as the endothelial cells and fibroblasts, to release mediators that induce dilation of the local microvasculature and cause __

Author: LEIGHTON DWIGHT OBILLOS



Answer:

. 1 (Tumor Necrosis Factor) TNFα and IL1 2 permeabilization of capillaries.


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