TOXICOLOGY: E. WHEN REPAIR FAILS

1 __ when the damage becomes too much; repair mechanisms are unable to repair the injury as when necessary enzymes or cofactors are consumed

2 Some types of toxic injuries cannot
be repaired effectively, as occurs
when xenobiotics are __

3 repair contributes to toxicity:

Question

E. WHEN REPAIR FAILS

1 __ when the damage becomes too much; repair mechanisms are unable to repair the injury as when necessary enzymes or cofactors are consumed

2  Some types of toxic injuries cannot
be repaired effectively, as occurs
when xenobiotics are __

3 repair contributes to toxicity:

LEIGHTON DWIGHT OBILLOS · Accepted Answer

.

1 Repair fails

2 Covalently bound to proteins

3) 
1 Excessive amounts of NAD+ are cleaved by PARP,
2 Too much NAD(P)H is consumed for the
repair of oxidized proteins and endogenous reductants

E. WHEN REPAIR FAILS 1 when the damage becomes too much; repair mechanisms are unable to repair the injury as when necessary enzymes or cofactors are consumed 2 Some types of toxic injuries cannot be repaired effectively, as occurs when xenobiotics are 3 repair contributes to toxicity: