F. TOXICITY RESULTING FROM DYSREPAIR 3) Carcinogenesis ; a) Failure of DNA Repair: Mutation, the Initiating Event in Carcinogenesis 1 Encode proteins that inhibit the progression of cells in the division cycle,which include cyclindependent protein kinase inhibitors, TFs that transactivate genes encoding cyclindependent protein kinase inhibitors, and proteins that block TFs involved in DNA synthesis and cell