How is nicotine as ganglionic blocker?

It is a component of cigarette smoke, poison with undesirable effects, w/out therapeutic benifit and deleterious to health, highly addicitive. Causes release of dopamine in brain stimulating nicotinic receptors of Ach, gives people good feeling. Available as patches, lozenges, gums, other forms. Absorbed and effective in reducing craving for nicotine in people who wish to stop smoking, depending on the dose depolarizes autonomic ganglia, resulting first in stimulation then in paralysis of all ganglia. Nicotine receptors exist at CNS, participating in stimulant effect of the drug