What are risk factors of OA?

Obesity/metabolic disorder (main reversible cause, knee, hip and hand OA) Dietary intake and nutrients (antioxidants, vit C lower risk, vitD promising nutriment of OA) Age, Sex and Ethnicity (age best risk factor, women greater risk hand and knee OA) Sex Hormones (more in women menopause, estrogen) Occupational factors Joint Deformity/Laxity Joint Deformity Acute Injury and Joint loading (secondary OA especially ACL meniscus) Repetitive activities with joint overuse, Muscle weakness, genetics (Collagen II genes, matrix protein genes, vit D, estrogen receptors)