What are classic antidepressants?

Tricyclic AD's (Clomipramine, Imipramine, Amitriptyline, Nortriptyline, Desipramine, Doxepine) Actions (block reuptake pumps for NE, serotonin, serotonin 2A and 2C receptors and disinhibit DA and NE release. Overdose lethal, second-line for resistant depression) Side effects (Blockade of muscarinic cholinergic Rs M1 dry mouth, constipation and blurred vision, and M3 insulin action disruption. Histamine 1 Rs cause sedation and weight gain, a1 Adrenergic Rs cause orthostatic HTA, dizziness, and voltage-sensitive Na channels cause seizure, arrhythmia and arrest) Efficacy (acc to literature)