How is classification of myelodysplasia?

• Dysplasia may be in single lineage affecting red cells (refractory anemia, RA), WBC or Plt. Or can present in two or more myeloid lineages • Erythroid dysplasia can be associated with ring sideroblasts (RARS) • If the blast cell count is increased in the bone marrow, the diagnosis is refractory anemia with excess blasts (RAEB) • 5q-Syndrome is more common in women and typically with presents macrocytic anemia and thrombocytosis