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Hematology

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Question:

How is prevention of transfusion GVHD?

Author: H K



Answer:

To prevent TA-GVHD, blood products intended for immunocompromised recipients are often irradiated to eliminate donor T cells' proliferative capacity while maintaining their hemostatic function. Given the severity of TA-GVHD and its high mortality rate, prompt recognition, and supportive care are critical. Any suspicious cases should be reported promptly, and patients may require aggressive immunosuppressive therapy to manage the immunemediated damage


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H K
H K