What are key considerations in transplant in terms of complications?

Transplant approach affects immune recovery Cord blood, T-cell Depl., ATG use= prolonged IS Marked increase in viral reactivation/infection CMV, Adeno, EBV, HHV-6, HSV—surveillance essential Occurrence of aGHVD or cGVHD adds to risk Use of and dose of steroids critical risk factor Doses <1mg/kg and qod dosing can decrease risk Infection increases the risk of all complications we will discuss