What are medical side-effects of ketamine use?

Ketamine stimulates the cardiovascular system, due to decreased catecholamine reuptake. These changes lead to increased heart rate and blood pressure Patients with a history of chronic ketamine use commonly reported abdominal pain and urinary tract symptoms. A number of cases reports suggest that ketamine abuse can cause suprapubic pain, dysuria and hematuria Liver damage: caused by chronic use of ketamine: bile duct dilatation, microscopic bile duct injury, and even significant liver fibrosis