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Pharmacology

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Question:

How is digoxin toxicity?

Author: H K



Answer:

Should be used with drugs slowing AV conduction (b blockers, verapamil, diltiazim) GI (nausea, vomit, abdo pain) Neuro (weakness, confusion) Electrolyte (Hyperkalemia >5.5 poor prognosis) Cardiac (bradycardia, block) Therapeutic level is 0.8-2 ng/ml, toxic >2.4 ng/ml Severe toxicity leads to V tach needs antiarrhythmatics and antibodies to digoxin (immune Fab)


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H K
H K