What are therapeutic indications of SSRIs? pharmacokinetcs and adverse effects?

Depression, OCD, panic disorder, GAD, SAD PO, substrates for CYP metabolism and inhibitors of enzyme Effects (less severe than TCA, no arrhythmias, sexual dysfunction, change in weight, suicidal thoughts, serotonin syndrome (hyperthermia, tachcardia, sweating, myoclonic (if with MAOI), changed mental status) Disconitnuation syndrome (occurs w/abrupt withdrawal