What are MAO I?

Stable molecules w/MAO, inactivates it in brain, liver and gut Antidepressant action is delayed several weeks, include Phenelzine, Tranylypromine, Selegiline Indications (unresponsive/ allergic to TCAs) Adverse effects (drug-food interaction like tyramine lead to HTA and arrythmia Drug-drug intreraction (not w/SSRIs since life threat serotonin syndrome