Question:
What is tx of simple renal colic?
Author: H KAnswer:
✔ Non-steroidal anti-inflammatories: - Two mechanisms of action: ● They block the cyclo-oxygenases involved in the inflammatory cascade. They reduce local edema and inflammation and lead to relaxation of the smooth muscle fibers of the ureter, thus reducing (decreasing) peristalsis. ● They decrease the glomerular filtration rate. Analgesics: • Level 1 (paracetamol): in combination with NSAIDs in case of low intensity pain. • Level 3 (morphine):in case of contraindication to NSAIDs. In combination with NSAIDs in the case of significant pain. In case of resistance to NSAID therapy., To be used in the form of IV titration of morphine hydrochloride. Water restriction if painful phase, urine seiving
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