What are prognostic factors of RCC?

Pathologic stage has proven to be the single most important prognostic factor for RCC Lymph node involvement has long been recognized as a dire prognostic sign, as it is associated with 5- and 10-year survival rates of 5% to 30% and 0% to 5%, respectively Tumor size :less than 4 cm better prognosis Nuclear grade and histologic subtype