How is sepsis, bacteremia and septic shock by pyelonephritis?

- Although bacteremia can be transient, self-limited, and, therefore, of little clinical significance , sepsis constitutes a medical emergency . - Can be due mainly to Gram negative organisms but also to Gram positive , fungi as well as viruses - Can be lethal in 13% in case of septic syndrome without shock and up to 43% in case of shock developing after a septic syndrome