How is adj tx of pancreatic cancer?

5-Fu combination + radiation Gemcitabine combination Better but more toxic Needed more study Neonatal adj: Adv. Dec. the tumor burden at operation Inc. rate of resectability Killing some Tu. Cell before spread intraop. Buying time Make Pt with Occult Metas.Dz , shown. Less Futile surgery. By evi. : not inc. Morbidity /mortality May dec. rate of Pancreatic fistula BUT no survival advantage