How is recurrent angioedema?

• Without urticaria may be due to C1 esterase deficiency (protease inhibitor of the complement system) • There is often a family history of similar problems. • It may also be caused by angiotensin converting enzyme (ACE) inhibitors such as captopril, quinapril, enalapril and others, which are used to treat heart failure and hypertension. These drugs inhibit kinin breakdown • Angioedema may also be idiopathic