How is histopathology of small cell carcinoma?

• full-thickness epidermal replacement by crowded keratinocytes that demonstrate disordered dyspolarity, loss of maturation, and nuclear pleomorphism with hyperchromasia • Apoptotic or dyskeratotic cells as well as typical and atypical mitosis are present at all levels of the epidermis, as seen in the following image • Variable loss of the granular layer with surface parakeratosis • Involvement of hair follicles is common