How is metastasis for small cell carcinoma?

• Squamous cell carcinoma (SCC) metastases are usually discovered 1-2 years after diagnosis • Primary tumors spread along fascial planes and nerves, as well as through lymphatics and blood vessels • Ipsilateral regional nodes (submental, submandibular, and parotid) are the most common metastasis recipients with a rate of 80% • Distant metastases occur in 14.8% of metastatic squamous cell carcinoma (SCC) and most commonly involve the lungs, liver, brain, skin, or bone • Bowen disease invades the dermis in 3-4% of cases, with a higher rate of 10-14% in anogenital locations