What is drug-induced HS syndrome?

• Syn. Drug related eosinophilia with systemic syndrome (DRESS) • Skin eruption with systemic symptoms and internal organ involvement (heart, kidney, liver) • Typical signs and symptoms: exanthem, erythematous centrofacial swelling, fever, malaise, lymphadenopathy, ad involvement of other organs (liver, kidneys) • >70% have eosinophilia • Liver function tests (LFTs) abnormalities and/or hepatosplenomegaly are helpful diagnostic clues