What are lab results of Pemphigus?

• DIF: IgG deposited on the surface of the keratinocytes in and around lesions. IgG1 and IgG4 are the most common subclasses • Complement components such as C3 and Ig M are present less frequently than IgG. DIF shows intercellular deposition throughout the epidermis • IDIF: presence of circulating IgG that bind to epidermis (80-90% of patients with pemphigus vulgaris). The titer of circulating antibody correlates with disease course