Dermatology: What is Pemphigoid Gestationis?

Question

What is Pemphigoid Gestationis?

H K · Accepted Answer

• Pemphigoid gestationis (PG) is a rare autoimmune 
bullous dermatosis of pregnancy
• Most patients develop antibodies against 2 
hemidesmosomal proteins, BP180 (BPAG2, collagen 
XVII) and less frequently BP230
• Strong association with HLA-DR3 (61-80%) and HLADR4 (52%) (combination)

Dermatology

What is Pemphigoid Gestationis?

• Pemphigoid gestationis (PG) is a rare autoimmune bullous dermatosis of pregnancy • Most patients develop antibodies against 2 hemidesmosomal proteins, BP180 (BPAG2, collagen XVII) and less frequently BP230 • Strong association with HLA-DR3 (61-80%) and HLADR4 (52%) (combination)

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