Question:
How is mantle cell lymphoma?
Author: H KAnswer:
Tumor cells closely resemble the normal mantle zone B cells that surround germinal centers Painless adenopathy Small lymphocytes with cleaved contours Express high levels of cyclin D1 t(11:14) • Monotonous small to medium-sized cells, indented nuclei • IHC: CD20+, CD5+, Cycline D1+
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Author
H K