What is angiosarcoma?

• Angiosarcoma is the most common primary malignancy (non-lymphoid) of the spleen. • Older patients • Prognosis is poor and most patients die within 1 yr of diagnosis • The tumor shows anastomosing vascular channels lined by atypical endothelial cells. • It may also exhibit solid or papillary growth patterns. • Highly atypical cells lining the vascular spaces. • IHC: CD31, CD34 positive