What is normal distribution of BM?

• The hematopoietic cells are present as cords between vascular sinusoids and are supported by a framework of branching processes of fibroblasts and reticulin fibers. • Erythroid precursors are present as clusters (islands) and are closely associated with centrally placed sinusoids. • Megakaryocytes, the largest of the hematopoietic cells, are closely apposed to the walls of the sinusoids. • Lymphocytes and plasma cells are mostly present around capillaries and arterial vessels • Early granulocyte precursors are located close to the bony trabecule • Mature granulocytes are located more centrally, between adjacent trabeculae