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Question:

How is morphology of leydig cell tumor?

Author: H K



Answer:

➢ Neoplastic Leydig cells have an appearance that is similar to their normal counterparts. ➢ Large in size, round or polygonal cell outlines, abundant granular eosinophilic cytoplasm, and a round central nucleus. ➢ Nests and clusters ➢ The cytoplasm frequently contains lipid droplets, vacuoles, or lipofuscin pigment, and, most characteristically, rod-shaped crystalloids of Reinke, (25% of the tumors). ➢ Many intervening capillaries, typical of endocrine tissue


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H K
H K