Question:
What are immature malignant teratomas?
Author: H KAnswer:
➢ Found early in life, the mean age at clinical detection being 18 years. ➢ They typically are bulky and appear solid on cut section, and they often contain areas of necrosis; ➢ Uncommonly, cystic foci are present that contain sebaceous secretion, hair, and other features similar to those of mature teratomas. ➢ On microscopic examination, the distinguishing feature is the presence of immature elements or minimally differentiated cartilage, bone, muscle, nerve, or other tissues. ➢ As with other tumors, the prognosis depends on grade and stage.
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H K