What are complications of sclerosing cholangitis?

Cirrhosis. Cholangitis. Obstructive jaundice. Cholangiocarcinoma (10%). Primary sclerosing cholangitis is one of the major known risk factors for cholangiocarcinoma . This represents a 400-fold greater risk of developing cholangiocarcinoma compared to the general population.   Surveillance for cholangiocarcinoma is mandatory