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Question:

How is CT in glomerular histologic lesions? Distribution of lesions?

Author: H K



Answer:

➢Irregular thickening of GBM in response to the presence of extramembrane deposits ➢ Duplication of GBM (“MPGN"). ➢Glomerulosclerosis: increase in the mesangial matrix ("Diabetes") ➢Focal/diffuse lesions : Focal lesions affect only a minority of the glomeruli. Diffuse lesions affect all glomeruli in the same way. ➢Segmental/global lesions: The lesion is said to be Segmental when only part of the glomerular capillary is affected. The lesion is said to be global when it affects the entire affected glomerulus


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H K
H K