What is oligoderndroglioma?

➢ Account for 5% to 15% of gliomas and most commonly are detected in the fourth and fifth decades of life ➢ MRI image shows a mass usually well circumscribed, with cystic areas and focal calcification. ➢ It enhances as a result of the rich vascular network of anastomosing capillaries within the tumor. ➢They typically occur within the cerebral hemispheres, usually in white matter, of adults in their 30s and 40s. ➢ Typical oligodendrogliomas have round blue nuclei with clear cytoplasm (WHO II) ➢ Most have cytogenetic abnormalities involving chromosomes 1p and 19q. ➢ They tend to be slowly progressive over years and can have a better prognosis than other adult gliomas