How is dx of IT? Tx?

➢ The diagnosis of ITP is a diagnosis of exclusion. ➢ First, it has to be determined that there are no blood abnormalities other than a low platelet count, and no physical signs other than bleeding. ➢ Then, secondary causes (5–10 percent of suspected ITP cases) should be excluded. tx: ➢ Corticosteroids remain the drugs of choice for the initial management of acute ITP. ➢ If 6 months of medical management (Corticosteroids, IV immunoglobulin (IVIG)…) fails to increase the platelet count to a safe range (about 30,000/µL), removal of the spleen (the organ in which the main clearance of red cells, platelets, and leukocytes occurs) becomes an option.