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Clinical Immunology

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Question:

How is allergic contact dermatitis to rubber?

Author: H K



Answer:

➢ ACD to rubber is caused by a type IV reaction and is the result of exposure to the accelerators present in rubber products in sensitive individuals. ➢ ACD due to synthetic rubber gloves occurs even with the use of latex-safe products. (Individuals may have ACD to chemicals added to rubber gloves). ➢ An allergic reaction to vinyl gloves is not likely and is considerably rare ➢ Individuals experiencing this type of reaction typically develop localized erythema, pruritus, and urticarial lesions 48 hours after exposure. ➢ Incorrectly labelling this problem as latex allergy and recommending nonlatex rubber substitutes (eg, hypoallergenic gloves) likely will not be effective, as these nonlatex replacement products contain the same accelerators as do latex gloves.


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H K
H K