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Clinical Immunology

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Question:

What are tests for celiac disease?

Author: H K



Answer:

Before a physician performs an intestinal biopsy, blood work are ordered as part of the screening process. Before the blood work, the patient must eat glutencontaining foods for a certain period of time to achieve more accurate results. ➢ These patients have antibodies to gliadin, as well as autoantibodies to endomysium, reticulin, and tissue transglutaminase (the antibody trinity of coeliac disease). ➢ The blood tests considered most effective to indicate possible celiac disease include tissue transglutaminase antibody (tTG) immunoglobulin A (IgA) and total IgA. ➢ The IgA test is performed because an IgA deficiency is common in celiac patients.


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H K
H K