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Clinical Immunology

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Question:

What is role of cytokines in innate antiviral immunity?

Author: H K



Answer:

IFN a: Produced by infected cell Inhibits viral infection: Induces enzymes that are able to degrade viral RNA or inhibit viral protein synthesis Increases MHC-I expression to facilitate recognition of infected cell by CTL Activates NK cells IL2, IFN-g : activate B cell and Tc IFN-g and TNF-b activate macrophages


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H K
H K