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CNS Pharmacology

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Question:

Barbiturates precaution

Author: Suzuki



Answer:

3. Precautions: barbiturates induce the CYP450 system and, therefore, may decrease the duration of action of drugs that are metabolized by these hepatic enzymes. Barbiturates increase porphyrin synthesis and are contraindicated in patients with acute intermittent porphyria.


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Suzuki
Suzuki