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CNS Pharmacology

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Question:

Eszopiclone

Author: Suzuki



Answer:

Eszopiclone is an oral nonbenzodiazepine hypnotic (also using the BZ1 receptor similar to zolpidem and zaleplon) and is also used for treating insomnia. Eszopiclone been shown to be effective for up to 6 months compared to a placebo. Eszopiclone is rapidly absorbed (time to peak, 1 hour), extensively metabolized by oxidation and demethylation via the CYP450 system, and mainly excreted in urine.Elimination half-life is approximately 6 hours.


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Suzuki
Suzuki