III. SELECTIVE SEROTONIN REUPTAKE INHIBITORS

Are a group of chemically diverse antidepressant drugs that specifically inhibit serotonin reuptake, having 300- to 3000-fold greater selectivity for the serotonin transporter, as compared to the norepinephrine transporter. it exhibit little ability to block the dopamine transporter muscarinic, α-adrenergic, and histaminic H1 receptors.