B. Carbamazepinemechanism and use

Carbamazepine reduces the propagation of abnormal impulses in the brain by blocking sodium channels, thereby inhibiting the generation of repetitive action potentials in the epileptic focus and preventing their spread. Carbamazepine is effective for treatment of partial seizures and, secondarily, generalized tonic-clonic seizures. It is also used to treat trigeminal neuralgia and bipolar disorder.