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CNS Pharmacology

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Question:

C. Monoamine Oxidase Inhibitors Mechanism—

Author: Suzuki



Answer:

Selegiline and rasagiline are selective inhibitors of monoamine oxidase type B, the form of the enzyme that metabolizes dopamine. Hepatic metabolism of selegiline results in the formation of desmethylselegiline (possibly neuroprotective) and amphetamine.


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Suzuki
Suzuki