Question:
Roles of accessory cells in immune response?
Author: Shay 1vccAnswer:
Accessory cells are nonlymphoid cells such as macrophages, dendritic cells, and Langerhans cells (epithelial dendritic cells) that function to present antigens to MHC-restricted T cells. Stromal cells – “Nurse” cells in the bone marrow. Facilitate blood cell development by providing a tethering substrate for proliferating progenitor cells as well as providing growth factors and chemical signals for development and proliferation Endothelial cells-Make up the linings of blood vessels. Express adhesion molecules to which circulating blood cells anchor and migrate through the vessels into infected tissue.
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