level: level 2
Questions and Answers List
level questions: level 2
| Question | Answer |
|---|---|
| when do nitriles reduce to give primary amines | on reduction with lithium aluminium hydride or catalytic hydrogenation |
| what are the catalysts used in reduction of nitriles | H2/Ni Na(Hg)/C2H5OH |
| what are nitriles | R-CN |
| what are amides | R-CO-NH2 |
| reduction of amides gives amine | LiAlH4 and H2O |
| gabriel phthalimide synthesis | it is used to prepare primary amine |
| phthalimide on treatment with ethanolic potassium hydroxide forms | potassium salt of phthalimide |
| how do you get N-alkylphthalimide from potassium salt of pthaminide | by heating with alkyl halide |
| why can't aromatic primary amines be prepared from it | because aryl halides do not undergo nucleophilic substitution with anion formed by phthalmide |
| what is the next step after formation of N-alkylphthalimide | add aq NaOH |
| what is the hoffmann bromamide degradation reaction | preparation of primary amines by treaing an amide with bromine in an aqueous or ethanolic solution of NaOH |
| what is the odour of lower aliphatic amines | fishy odour |
| what is the order of solubility of amines | it decreases with increase in molar mass due to increase in size of the hydrophobic alkyl part |
| amines are soluble in | organic solvents like alcohols |
| what is the order of boiling point for amines | primary >secondary>tertiary |
| why is the boiling point of primary amines high | because of steric hinderance |
| what makes amines reactive | diff. in E.N. b/w N and H atoms and the presence of unshared pair of electrons on N |
| how do amines behave and why | as nucleophiles due to the presence of unshared electon pair on nitrogen |
| basic character of amines | react with acid to form salts |
| amines reaction with base like NaOH | they regenarate to parent amines |