ability to perform work
• Energy cannot be created or destroyed, only
transferred | Energy |
process of converting food into biologically useful forms of energy | Bioenergetics |
how much heat is released when a food is combusted?
• Measured by increase in water temp around chamber
• kcal/Calorie = increase 1kg water 1°C | Bomb calorimetry |
• carbohydrates
• protein
• fat
• alcohol | What provides energy (ATP)? |
24 hour dietary recall, food frequency questionnaire | Retrospective |
diet record (manual or computer calculated) | Prospective |
People tend to overestimate activity and underestimate intake, can be up to 30%! | Problem with measuring calorie intake |
Total Energy Expenditure = resting metabolism + thermic effect of food + physical activity | 3 factors determine # of kcal used per day |
energy needed to keep the body alive | Resting metabolism |
energy used for digestion and absorption | Thermic effect of food |
energy used for activity
• this is where the most change can be made | Physical activity |
• measures body fat % through electric
current from one handle to the other
• fat is a poor conductor so more resistance = higher body fat %
• relatively inexpensive
• quick & painless
• most accurate if bladder is empty and hydration is normal | Bioelectric Impedance Analysis (measures body composition) |
• measures subcutaneous fat to
estimate total body fat
• uses calipers to measure 2-9 sites depending on procedure used
• relatively inexpensive
• need to be well-trained to measure
• not as accurate for obese or elderly individuals | Skinfold Thickness (measures body composition) |
• weigh on land and in water
• difference due to body volume and density
• standardized equations to calculate fat- free mass
• very accurate if done correctly
• very expensive equipment & not easy to use
• can be frightening to use | Underwater Weighing (measures body composition) |
• same principles as underwater weighing but
displaces air instead of water
• equally accurate
• more convenient
• expensive | Plethysmography (Bod Pod) (measures body composition) |
• less invasive than most methods
• more expensive than most methods • very accurate | Radiologic Methods (measures body composition) |
Dual-energy X-ray absorptiometry (DXA or DEXA)
CT scan or MRI | Other Methods to Assess Body Composition |
measuring waist circumference
• Men < 102 cm
• Women < 88 cm | Estimate visceral fat by |
Higher incidence of:
• heart disease
• high blood pressure • stroke
• diabetes | Risk associated with visceral fat |
more visceral fat
higher risk of weight-related health problems | Apple Shape |
less visceral fat
lower risk of weight-related health problems | Pear Shape |
1. Physiological factors
2. Food production & consumption
3. Physical activity & psychosocial factors | What Dictates Body Composition |
Genetics
Epigenetics (how genes are expressed)
Medications
Hormones and Proteins
Metabolism
Gut microbiota | Physiological Factors (Body Composition) |
emotions
media influence
level of physical activity has decreased
environment
obesogenic environment | Physical Activity & Psychosocial factors |
two diseases or health conditions often occurring together | Comorbidity |
• depression
• severe mental disorder
• cardiovascular disease (heart failure, abnormal heartbeat)
• asthma
• COPD | associated with increased body weight |
• anxiety
• dementia
• cancers (lung, colon, prostate, breast) - conflicting studies here
• Type 1 diabetes | not associated with increased body weight |
• Some reduced risk of disease if underweight
• Need some weight for insulation and reserve for famine or illness
• May have difficulty fighting disease
• Suppressed immune system
• Affect electrolyte balances
• Delay development in children/adolescents
• Health complications for babies if mom is underweight | health issues with being underweight |
“negative attitudes, mistreatment, and discrimination based on weight status, particularly negative attitudes toward the obese” (p. 283) | Weight stigmatization |
measures associations between concepts and evaluations (in this case fat/thin and good/bad) | Implicit Association Test (IAT) |
Pancreas
Gall bladder
Salivary glands
Liver | Accessory organs |
Small intestine
Large intestine
Esophagus
Oral cavity, tongue, teeth
Stomach
Pharynx | Major subdivisions |
protein molecule that speeds up a reaction | Enzyme |
lining of GI tract; protective layer from stomach acid and other secretions needed to break down food | Mucosa |
after food is chewed, forms a bolus to swallow | Bolus |
wave-like movement of muscles to move food through esophagus | Peristalsis |
when bolus mixes with stomach acid, it format semi-liquid mass called chyme | Chyme |
rhythmic contractions in intestines to mix chyme and increase absorption | Segmentation |
projections in small intestine lining | Villi |
smaller, brush-like projections on the cell membrane of villi | Microvilli |
Simple diffusion
Osmosis
Facilitated diffusion
Active transport | 4 Methods of Absorption |
molecules move from high concentration to low concentration | Simple diffusion |
diffusion of water (depends on concentration of other substances on each side of cell membrane) | Osmosis |
carrier molecule helps move molecule from high to low concentration | Facilitated diffusion |
carrier molecule helps move molecule from low to high concentration but need energy (ATP) | Active transport |
dry mouth
Stimulants to encourage saliva production, saliva substitutes | Xerostomia |
stomach acid leaking back into esophagus
Eat smaller meals, avoid spicy/fried/fatty foods, stay upright after eating | Heartburn |
mucosa layer of stomach or esophagus erodes, exposes tissue to stomach acid | Ulcers |
affects ability to digest & absorb if not getting enzymes needed | Pancreatic & gallbladder problems |
related to intestinal issues | Diarrhea & constipation |
Three systems:
Creatine phosphate
Anaerobic glycolysis
Oxidative phosphorylation | How Do We Rephosphorylate ADP? |
Creatine phosphate
can be synthesized in liver & kidneys from amino acids | What is used to rephosphorylate ATP |
Breaks down carbohydrate (glucose) to form ATP | Anaerobic Glycolysis System |
is a number from 0 to 100 assigned to a particular food, with pure glucose being 100, which represents the relative rise in blood glucose levels 2 hours post consumption. | Glycemic index or GI |
6 carbon, 12 hydrogen, 6 oxygen
Glucose: usually found in disaccharides & polysaccharides
Fructose: found in fruits & veggies, sweeteners
Galactose: found in disaccharide only | Monosaccharides |
2 monosaccharides together
Sucrose: found in fruits, veggies, honey, maple syrup, sugar cane
Lactose: found in diary products
Maltose: found in some Asian foods (maltose syrup), beer, fermented drinks | Disaccharides |
More than 10 monosaccharides | Polysaccharides |
Endosperm - starch
Bran layers - fibre
Germ - vitamins & minerals | Whole grains |
mostly endosperm | Refined grains |
at least half of grain servings are whole grain | Grain Recommendations |
Insulin (released from beta cells)
Glucagon (released from alpha cells) | Regulation of blood glucose by pancreatic hormones |
blood glucose rises
pancreas releases insulin
insulin stimulates muscles and liver to take in glucose
promotes storage of glucose as glycogen and storage of fats and protein | Glucose Regulation in the Body - After eating carbohydrates |
blood glucose drops
pancreas releases glucagon
glucagon stimulates liver to release stored glucose
muscles can use stored glucose
stimulates release of fats and protein to be converted to glucose | Glucose Regulation in the Body - After After fasting |
effect of a carbohydrate on blood glucose level | Glycemic response |
ranking of how a food affects glycemic response | Glycemic index (GI) |
legumes, beans, apples, milk | low GI foods |
oranges, bananas, sweet potatoes, ice cream, many yogurts | moderate GI foods |
refined grains, starchy veggies (ex. potatoes), white bread, white rice, many cereals | high GI foods |
is the primary structural and functional component of every cell in the human body. | Protein |
Contains carbon, hydrogen, & oxygen + nitrogen
Formed from amino acids
20 amino acids | Chemical Composition of Protein |
9 | How many essential amino acids |
4 | How many nonessential amino acids |
7 | How many conditionally essential amino acids |
are the essential amino acids leucine, isoleucine and valine
These comprise 35% of our body’s muscle protein
Act as the building blocks of protein | BCAA’s |
animal proteins
some non-animal sources (soy, quinoa, chia) | Examples of complete proteins |
plant proteins | Examples of incomplete proteins |
growth (incl. brain development)
skin integrity
fertility
structure and function of cell membranes
promote blood clotting | Essential fatty acids are important for |
Good source of essential fatty acids
Regular fish consumption reduces risk of death from heart disease | Benefits of seafood consumption |
Not all fish have high amounts of essential fatty acids
Mercury and other toxins can contaminate
Fish farms
Risks of consuming raw fish | Risks of seafood consumption |
produces bile | Liver |
stores bile
secretes bile as needed | Gall bladder |
pancreatic lipase secreted | Pancreas |
shape to body
stored energy
insulate body from temperature changes
protect internal organs against physical shock
creating hormones | Functions of fat in the body |
bile salts, vitamin D, and several hormones, including the sex hormones (estrogen, androgen, and progesterone) as well as cortisol | Cholesterol is used for the production of |
breaking down triglycerides into fatty acids + glycerol | Lipolysis |
breaking down fatty acids to convert to acetyl-CoA | Beta-oxidation [2] |
prolonged fasting
very low CHO diet
strenuous exercise
type I diabetic | Ketosis: high level of ketones in blood
happens when: |
dry, scaly skin
liver abnormalities
poor wound healing
growth failure in infants
impaired hearing and vision | Not enough essential fatty acids in diet
Symptoms include: |
Consuming omega-3 and omega-6 polyunsaturated fats
Consuming monounsaturated fats
Consuming plant foods
Adequate intake of B vitamins
Moderate alcohol consumption | Reducing Risk of Heart Disease - Dietary factors |
Quit smoking
Exercise
Reduce waist circumference
Lose weight if overweight
Control diabetes & high blood pressure | Reducing Risk of Heart Disease - Lifestyle factors |
Saturated fats: less than 10% of diet
Trans fats: less than 1% of diet
Cholesterol: less than 300mg per day
Generally: 1.0 g/kg body weight | Fat recommendations |
less than 0.5g | Fat free |
less than 3g | Low fat |
25% less than comparable product | Reduced or less fat |
less than 0.2g + less than 0.2g trans fat | Saturated fat free |
less than 2g + max 15% kcal from sat. fat | Low saturated fat |
25% less than comparable product (& no increased trans fat) | Reduced or less saturated fat |
Not enough total kcal for workout/recovery needs
Not enough fat to replace intramuscular fat stores
Negative impact on manufacture of sex-related hormones
Decline in HDLs
Not enough vitamin A, D, E, K (fat-soluble) | If fat is too low |
Biological sex
Weight
Medications
Drinking on empty stomach vs. eating while you drink
Chugging vs sipping
Health concerns (enzyme deficiencies) | Factors that affect how alcohol is and absorbed and metabolized |
10 drinks a week for women, with no more than 2 drinks a day most days
15 drinks a week for men, with no more than 3 drinks a day most days | Reduce your long-term health risks by drinking no more than: |
5 oz. wine
10 oz. wine cooler
12 oz. beer
8-9 oz. malt liquor
1.5 oz. hard liquor | 1 drink = |
live longer
decreased risk of cardiovascular disease (antioxidant resveratrol found in grapes?)
increase HDLs
could be related to SES and education levels | In moderate amounts, alcohol consumption may have some benefits: |
13 essential | How many vitamins are there? |
mostly absorbed right into the blood
little to no storage available
usually excess is excreted | Water soluble |
requires fat to be absorbed
not as easily excreted (usually can be stored) so typically more risk for toxicity
since can be stored will be better able to accommodate for fluctuations in intake | Fat soluble |
Elements needs by the body in small amounts for health & tissue maintenance
Provide no energy (Calories) but essential in the body | What are Minerals? |
Calcium
Chloride
Magnesium
Phosphorus
Potassium
Sodium | Macro (major) minerals: more than 100 mg/day |
Chromium, Copper, Fluoride,
Iodine, Iron, Manganese
Molybdenum, Selenium,
Zinc | Micro(minor) minerals: less than 100 mg/day |
Most absorptions happens in the small intestine
*fat (bile) is needed for absorption of fat soluble vitamins | Vitamin & Mineral Digestion |
Age, Gender, Life Cycle Stage
Genetics, general and gastrointestinal (GI) health,
food in GI tract, presence of other vitamins and minerals,
form of the mineral | Many factors can influence absorption levels |
restricted diets due to allergies or food preferences
restricted Calorie intake means you may not get enough food to get the variety of nutrients needed
infants and children
when pregnant & breastfeeding
older adults tend to absorb less
certain medications can reduce absorption
smokers and heavy alcohol users
living in northern climates, being covered up outdoors, or having darker skin pigmentation | Situations where supplements might be needed |
adding back in something lost in processing, like vitamins back in that were lost in grain processing | enrichment |
adding nutrients that are not generally found in that product | fortification |
adding iodine to table salt
adding vitamin D to milk
adding folic acid to grain products | Examples of Fortification |
women=700 men=900mcg upper limit 3,000mcg Lack of growth, night blindness, more frequent and severe infections | Vitamin requirements and Symptoms of deficiency- Vitamin A |
15-20 mcg Joint pain, muscle spasms | Vitamin requirements and Symptoms of deficiency - Vitamin D |
15mg, upper limit 1000mg Muscle weakness | Vitamin requirements and Symptoms of deficiency - Vitamin E |
2.4mcg, no upper limit and Fatigue, numbness | Vitamin requirements and Symptoms of deficiency - Vitamin B12 |
women=75 men=90mg, additional 25mg if you smoke, upper limit of 2000mg and Poor wound healing, bleeding gums | Vitamin requirements and Symptoms of deficiency- Vitamin C |
1,000 – 1,200 mg Osteoporosis, muscle spasms | Mineral requirements and Symptoms of deficiency - Calcium |
8-18 mg Fatigue, loss of appetite, reduced resistance to infection | Mineral requirements and Symptoms of deficiency - Iron |
8-11 mg Impaired growth, poor immunity | Mineral requirements and Symptoms of deficiency - Zinc |
1,500 mg Not likely | Mineral requirements and Symptoms of deficiency - Sodium |
150 mcg Mental retardation, impaired growth and development | Mineral requirements and Symptoms of deficiency - Iodine |
positively and negatively charged ions that conduct an electrical current in a solution | Electrolytes |
upper limit = 2,300 mg | Daily sodium upper limits |
upper limit = 3,600 mg | Daily Chloride upper limits |
very unlikely, can happen during
severe vomiting or diarrhea
endurance sports if not replacing electrolytes during and after
nausea, dizziness, muscle cramps
if not treated can lead to coma | What happens if you have too little Sodium? |
increases risk of high blood pressure (hypertension)
high blood pressure increases risk for stroke & cardiovascular disease | What happens if you have too much Sodium? |
very unlikely
failure to thrive in infants | What happens if you have too little Chloride? |
very unlikely to report symptoms
some reported toxicity with extremely excessive amounts of table salt
vomiting
muscle weakness
severe dehydration | What happens if you have too much Chloride? |
table salt
fish
meat
milk
Eggs | Common sources of chloride |
Defined by resting blood pressure greater than 140/90 mmHg | hypertension (high blood pressure) |
Less than 5mg sodium per serving | Sodium-free, salt-free |
Less than 140mg sodium per serving | Low sodium |
25% less sodium per serving than reference product | Reduced/less/lower in salt or sodium |
No salt added during processing | No salt added, unsalted |
50% less added sodium per serving than reference product | Lightly salted |
4,700 mg
No upper limit | Potassium Daily recommendations: |
vegetables, especially leafy, green ones
dried beans, peas, nuts
orange juice
bananas
melons
potatoes
milk & yogurt | Good sources of potassium: |
Very rare, usually excreted through urine
Toxicity (too much) usually due to impairment with excretion or excessive supplementation
Hyperkalemia: risk of irregular heartbeat (cardiac arrhythmia) | What happens if you have too much Potassium? |
Rare, can occur with excessive vomiting or diarrhea, or excessive use of diuretics
Excess water loss can result in too much potassium loss and low blood potassium, called hypokalemia
contributes to hypertension (high blood pressure)
can increase calcium loss from bones | What happens if you have too little Potassium? |
centre of hemoglobin
hemoglobin is part of red blood cell
red blood cells transport oxygen & carbon dioxide | What does iron do? |
heme sources (more easily absorbed): animal meat
nonheme sources (less easily absorbed): beans, legumes, green leafy vegetables, animal milks, eggs, fortified grains
vitamin C can enhance absorption of nonheme iron | What are good sources of iron? |
Women (over 50 years old) and men (all ages)
RDA: 8mg
UL: 45mg
Women (19-50 years old)
RDA: 18mg
UL: 45mg | Iron daily recommendations |
gastrointestinal distress
hemochromatosis: excess iron in liver, leads to liver dysfunction | What happens if you have too much Iron? |
anemia: fatigue, loss of appetite, increased risk of infection, difficulty concentrating | What happens if you have too little Iron? |
animal products
fortified plant products: meat & egg replacements are required to have added B12
can store up to several years worth in the liver | Sources of B12 |
coenzyme in ATP production in the Citric Acid Cycle
forms a coenzyme with folate needed for red blood cell production | What B12 does: |
no known symptoms | What happens if you have too much b12? |
fatigue, sleep disturbance, numbness, memory loss
pernicious anemia: anemia due to low dietary B12 or poor absorption
more frequently occurs in vegetarians/vegans & elderly | What happens if you have too little B12? |
1.3 mg (under 50 years old, male & female)
1.5 mg (over 50 years old, female)
1.7 mg (over 50 years old, male)
UL = 100 mg | Daily recommendations Vitamin B6 |
Chicken, Pork, Lentils, Brown rice
Whole grains, Bananas, Broccoli,
Spinach, Meal & egg replacements | Sources of Vitamin B6 |
fatigue
difficulty walking
numbness
depression | What happens if you have too much Vitamin B6? |
microcytic anemia: red blood cells are light in color and small, can’t deliver oxygen efficiently
fatigue, headaches, confusion, poor growth
very rare if normally fed | What happens if you have too little Vitamin B6? |
Blood clotting
Part of reaction that binds protein to calcium (increase bone strength) | Role of vitamin K |
Women: 90 mcg
Men 120 mcg
No upper limit | Daily recommendations for Vitamin K: |
fish oils, legumes, green leafy vegetables
some is synthesized in large intestine but not enough | Dietary sources of vitamin K |
Nothing | What happens if you have too much of Vitamin K? |
abnormal blood coagulation (clotting)
newborns have less vitamin K available and can develop vitamin K deficiency bleeding which can be very severe
infants are given vitamin K at birth
may happen if you have problems absorbing fats
can also happen if you take antibiotics for a long time - can kill bacteria that produce vitamin K in the large intestine | What happens if you have too little of Vitamin K? |
Used to metabolize (break down) amino acids
Used to form red blood cells
Required for normal growth and development | Folate (Folic acid) |
400 mcg
600 mcg per day if pregnant or trying to get pregnant
upper limit: 1,000 mcg | Daily recommendation for folate (folic acid) |
leafy green vegetables
whole grains
fortified grains
orange juice
lentils
organ meats | Dietary sources of folate |
high folate intake has little risk but can mask a B12 deficiency
untreated B12 deficiency can cause irreversible nerve damage
may be related to small increase in risk of some cancers - may stimulate growth of pre-existing cancer cells | What happens if you have too much folate? |
increased risk for anemia, heart disease, and depression
during pregnancy can cause spina bifida in fetus | What happens if you have too little? |
is a neural tube defect where the spine does not properly form | Spina bifida |
donate an electron to neutralizes the free radical so it doesn’t cause cell damage | Antioxidants |
Retinoids come from animal sources: liver, fish oil, milk & milk products, eggs.
Carotenoids come from plant sources: dark orange fruits and vegetables, leafy green vegetables | Vitamin A sources |
vision health
bone and tooth development
immune system function
some carotenoids are antioxidants
regulates gene expression | What Vitamin A does: |
hypervitaminosis A: nausea, vomiting, dizziness, lack of coordination, blurred vision, birth defects, liver failure, death
hypercarotenemia: orange hands and feet from too much carotenoids | What happens if you have too much Vitamin A? |
blindness, more severe infections, lack of growth in children
can be an absorption issue if not enough fat intake | What happens if you have too little Vitamin A? |
citrus fruits
cabbage family
vegetables, especially leafy veggies | Common dietary sources Vitamin C |
helps with iron, copper, and chromium absorption
helps with synthesis of some amino acids and hormones
helps with collagen (a protein) formation: part of connective tissue (including skin, bones, teeth, cartilage & tendons) | What does Vitamin C do? |
gastrointestinal (GI) problems (nausea, diarrhea, vomiting)
kidney stones | What happens if you have too much Vitamin C? |
-scurvy: bleeding gums, bruising, poor wound healing, skin irritations
-rare in countries with good food supply; still seen in developing countries
-in countries with good food supply may be seen in alcoholics and people on very restricted diets | What happens if you have too little Vitamin C? |
seeds
nuts
oils
soybeans
dark green vegetables
whole grains | Common dietary sources Vitamin E |
fatigue
nausea | What happens if you have too much Vitamin E? |
very rare, may be due to absorption issue
anemia
muscle weakness | What happens if you have too little Vitamin E? |
Coenzyme for ATP production
Helps with synthesis of DNA and RNA
Helps with normal nervous system function | Thiamin (B1) |
pork
whole grains
legumes
tuna
soy products | Common dietary sources Thiamin (B1) |
Men = 1.2 mg
Women = 1.1 mg
No upper limit | Recommended daily intake Thiamin (B1) |
Nothing, will excrete excess | What happens if you have too much Thiamin (B1)? |
Beriberi: weakness, apathy, irritability, nerve tingling, poor coordination, paralysis, rapid heartbeat, congestive heart failure
Wernicke-Korsakoff syndrome | What happens if you have too little Thiamin (B1)? |
Coenzyme for ATP production
Helps with normal skin development | Riboflavin (B2) |
dairy, mushrooms, broccoli
asparagus, whole grains
leafy vegetables, red meat
poultry, fish | Common dietary sources Riboflavin (B2) |
Men = 1.3 mg
Women = 1.1 mg
No upper limit | Recommended daily intake Riboflavin (B2) |
Nothing, will excrete excess
May have bright yellow urine | What happens if you have too much Riboflavin (B2)? |
Ariboflavinosis: poor injury healing; inflammation of eyes, lips, mouth, and tongue; confusion
likely found in combination with other nutrient deficiencies | What happens if you have too little Riboflavin (B2)? |
Men: 16 mg
Women: 14 mg
Upper limit: 35 mg | Recommended daily intake Niacin (B3) |
Whole grains, Fortified flour
Meat, Fish, Poultry
Eggs, Milk, Nuts | Common dietary sources of Niacin (B3) |
flushed skin, tingling in feet & hands, rash, nausea, vomiting, high blood sugar, abnormal liver function, blurred vision
generally only happens if taking supplements, not likely from dietary sources
effective in lowering cholesterol if given in high doses (50 mg+) but often causes toxicity effects so can’t be tolerated | What happens if you have too much Niacin (B3)? |
Pellagra,which if not treated leads to the 4 D's | What happens if you have too little Niacin (B3)? |
Coenzyme for ATP production
Promotes transcription in protein synthesis | Pantothenic Acid (B5) |
meat
eggs
whole grains
legumes | Common dietary sources Pantothenic Acid (B5) |
5 mg
No upper limit | Recommended daily intake Pantothenic Acid (B5) |
Nothing, will excrete excess | What happens if you have too much Pantothenic Acid (B5)? |
Burning foot syndrome | What happens if you have too little Pantothenic Acid (B5)? |
Women (19-50 years old) and men (19-70 years old)
RDA: 1,000mg
UL: 2,500mg
Women (over 50 years old) and men (over 70 years old)
RDA: 1,200mg
UL: 2,000mg | Calcium Recommendations |
mineralization of bones and teeth
muscle contraction
nerve conduction
hormone and enzyme secretion | What does calcium do? |
milk & milk products
green leafy vegetables
fish with bones (e.g., salmon, sardines)
calcium fortified beverages | Where does calcium come from? |