Alendronic Acid: -Pathophysiology -Indicagtion -Interactions -Couselling -Side Effects

-Absorbed onto hydroxyappetite crystals in bone (slows rare of growth and dissolution)--> reduced bone turnover. - prophylaxis (long term/repeated streoid use)/ Long term established osteoporosis -Big molecule and chelatged with food and other drugs (struggles to be absorbed so little of drug is used by the body) -Take 30 mins before food, calcium and vitamin D after a different time to the drug, wiht a full glass of water sitting up right/ standing- gets to the stomach as quickly as possible to reduce risk of ulceration of oseophagus -Osteonercorsis of jaw (dentist review), Oseophageal reactions (oesoghagitis, uclers & strictures), Osteonecrosis of the external auditory canal.